
This cheesy beef enchilada tortellini skillet transforms classic Mexican flavors into an easy one-pan pasta dish that's ready in just 30 minutes. The combination of tender cheese-filled tortellini and seasoned ground beef, all smothered in enchilada sauce and melty cheese, creates a fusion comfort food that satisfies both pasta and Mexican food cravings.
I created this recipe during a busy week when I couldn't decide between Italian and Mexican for dinner. My family devoured it so quickly that it's now part of our regular rotation whenever we need comfort food fast.
Ingredients
- Ground beef: Adds hearty protein and pairs perfectly with the Mexican seasonings
- Cheese tortellini: Provides pillowy pasta pockets that catch the sauce beautifully
- Red enchilada sauce: Delivers authentic Mexican flavor without extra work
- Cheddar and Monterey Jack cheese: Create the perfect melty topping with complementary flavors
- Diced onion: Adds aromatic sweetness and texture to the beef
- Cumin, chili powder, garlic powder, salt, and pepper: Create that classic enchilada flavor profile
- Fresh cilantro or green onions: Brighten the rich dish with color and fresh flavor
Step-by-Step Instructions
- Cook Tortellini:
- Boil the tortellini according to package directions until they float to the top and are tender but still slightly firm. Be careful not to overcook as they'll continue cooking slightly in the skillet. A properly cooked tortellini should have a tender exterior with a slight bite in the center. Drain thoroughly to prevent excess water from diluting your sauce.
- Brown the Beef and Onions:
- Heat your largest skillet over medium heat until you can feel warmth when holding your hand above the surface. Add the ground beef and break it into small crumbles with a wooden spoon. Add the diced onion and cook together until the beef is no longer pink and the onions become translucent and soft about 5 to 7 minutes. Drain any excess fat to keep your dish from becoming greasy.
- Season and Combine:
- Sprinkle the cumin, chili powder, garlic powder, salt, and pepper evenly over the beef mixture and stir to coat every piece. Pour in the enchilada sauce and stir to combine allowing the flavors to meld for about 2 minutes. Gently fold in the cooked tortellini ensuring each pasta piece gets coated in the flavorful sauce without breaking the delicate pasta.
- Create the Cheese Topping:
- Evenly distribute both cheeses across the top of the skillet creating a blanket of dairy goodness. Cover with a tight fitting lid to trap the heat which will melt the cheese perfectly without drying out the dish. Wait patiently for 3 to 5 minutes until the cheese is completely melted and starting to bubble around the edges.
- Garnish and Serve:
- Sprinkle fresh cilantro or sliced green onions over the top just before serving to add a pop of color and freshness that balances the rich flavors. Serve immediately while the cheese is still gooey and the dish is piping hot.

This dish reminds me of Sunday dinners at my grandmother's house where she'd always experiment with combining cuisines. The enchilada sauce is truly the secret ingredient here. I remember the first time I made this, my husband asked for thirds and declared it better than traditional enchiladas because of the pillowy tortellini texture.
Make Ahead and Storage
This skillet dish keeps beautifully in the refrigerator for up to 4 days in an airtight container. The flavors actually improve overnight as the tortellini absorbs more of the enchilada sauce. When reheating, add a splash of water or chicken broth to loosen the sauce if it seems too thick. For meal prep, you can freeze individual portions for up to 3 months. Thaw overnight in the refrigerator before reheating for best results.
Easy Variations
Turn this into a vegetarian delight by substituting the ground beef with plant-based ground meat alternative or a mixture of black beans and corn. For a lighter version, use ground turkey or chicken instead of beef. If you prefer extra vegetables, add diced bell peppers, zucchini, or spinach during the cooking process. You can also adjust the heat level by choosing mild, medium, or hot enchilada sauce based on your family's preference.
Serving Suggestions
Complete this Mexican-Italian fusion meal with a simple side salad dressed with lime vinaigrette. For an authentic touch, serve with sliced avocado, a dollop of sour cream, or a sprinkle of crushed tortilla chips on top for extra crunch. This dish pairs wonderfully with a side of Mexican street corn or a simple cucumber and tomato salad to balance the richness of the cheese and beef.
The History Behind The Fusion
This recipe represents the beautiful marriage of Italian and Mexican cuisines, two culinary traditions that celebrate rich flavors and family-style dining. While tortellini originated in the Emilia-Romagna region of Italy, enchilada sauce has deep roots in Mexican cooking, dating back to Mayan times. This skillet dish honors both traditions while creating something uniquely American in its fusion approach. The combination might seem unconventional, but the cheese-filled pasta actually works perfectly with the spiced enchilada sauce.
Frequently Asked Questions
- → Can I use frozen tortellini for this dish?
Yes, frozen tortellini works perfectly. Simply follow the package instructions for cooking before adding it to the skillet.
- → How can I make this dish spicier?
To add more heat, you can use spicy enchilada sauce, add diced jalapeños, or increase the quantity of chili powder.
- → Can I substitute ground beef with another protein?
Absolutely! Ground turkey or chicken are excellent substitutes, or you can try plant-based alternatives for a vegetarian option.
- → What can I use instead of cheddar cheese?
You can swap cheddar with other meltable cheeses such as Colby, mozzarella, or a Mexican cheese blend for similar results.
- → Is this dish suitable for meal prep?
Yes, you can prepare it ahead of time and store it in an airtight container in the refrigerator for up to 3 days. Reheat it in a skillet or microwave before serving.