
Cheesy Penne Garlic Butter Beef is the kind of weeknight comfort food that gets rave reviews at my dinner table. Creamy, rich sauce wraps every bite of tender pasta and ground beef for a meal that truly satisfies. Finishing with lots of fresh parsley brings a pop of color and an irresistible aroma that reminds me of cozy Sunday feasts.
I came up with this dish on a night when all I wanted was something warm and filling but was short on time. My family loves how the beef and garlic butter transform ordinary pasta into something special. It has now joined our regular meal rotation.
Ingredients
- Penne pasta: This shape grabs onto sauce making every bite cheesy and satisfying. Choose quality bronze cut pasta for best texture.
- Ground beef: Brings hearty flavor and protein. Opt for eighty five or ninety percent lean for the best balance of taste and tenderness.
- Unsalted butter: Creates a velvety base for the garlic sauce. Use European style for extra creaminess if possible.
- Garlic (minced): Adds irresistible aroma and punch of flavor. Freshly minced garlic will always taste best.
- Onion powder: Provides a subtle depth and extra savoriness. Choose a good quality brand for full flavor.
- Italian seasoning: Infuses herbs like oregano and basil for a well rounded profile. Look for blends without added salt for better control.
- Salt and black pepper: Essentials for brightening flavors. Use sea salt or kosher and freshly cracked pepper for best results.
- Red pepper flakes: This is optional but adds a gentle heat and complexity. Use a pinch or more depending on your spice preference.
- Beef broth: Builds up sauce richness. Choose low sodium to control seasoning.
- Heavy cream: Adds wonderful lushness and helps the cheese melt smoothly. Go for full fat to achieve the silkiest sauce.
- Shredded mozzarella cheese: Melts into gooey deliciousness. Choose a block and shred it yourself for optimal melt.
- Grated Parmesan cheese: Brings a salty nutty finish and boosts the sauce’s body. Authentic Parmigiano Reggiano really elevates this.
- Chopped parsley: Freshens everything up right before serving. Always use fresh and chop just before sprinkling for the brightest flavor.
Step-by-Step Instructions
- Cook the Pasta:
- Fill a large pot with generously salted water and bring to a rolling boil. Cook the penne until just shy of fully tender so it holds its shape in the sauce. Drain thoroughly and set aside. Letting pasta sit too long after draining can cause sticking so a touch of olive oil can help.
- Sauté the Garlic:
- Melt the unsalted butter in a roomy skillet over medium high heat. Add the minced garlic and cook gently for about one minute. Stir constantly so the garlic does not brown. Only tender translucent garlic will release that signature aroma.
- Brown the Beef:
- In the same skillet, add the ground beef breaking it apart as it cooks for even browning. Take your time cooking until no pink remains as this develops big flavor. Drain off excess fat if there is too much so your sauce is not greasy.
- Season and Simmer:
- Season the beef thoroughly with onion powder, Italian seasoning, salt, black pepper, and red pepper flakes if you enjoy a kick. Stir well then pour in the beef broth and heavy cream. Let everything simmer gently for three to four minutes as the flavors meld and the sauce starts to thicken. It should look glossy and lightly creamy.
- Melt the Cheeses:
- Lower the heat and scatter in the mozzarella followed by the Parmesan. Stir slowly and continuously so the sauce becomes silky smooth. Making sure the cheeses melt fully is the key to a velvety finish.
- Combine Pasta and Sauce:
- Return the cooked penne to the skillet and use tongs to gently toss and coat every piece in that luscious cheesy sauce. Make sure the pasta is well covered and glossy for best results.
- Garnish and Serve:
- Scatter the freshly chopped parsley over the top and serve immediately. This herb really wakes up the whole dish.

Storage Tips
Transfer leftovers to an airtight container and refrigerate within two hours of cooking. The pasta will stay fresh for up to three days. Reheat gently on the stove or in the microwave adding a splash of beef broth or cream if needed to bring back the creaminess. I do not recommend freezing as the sauce may turn grainy and separate after thawing.
Ingredient Substitutions
If you are out of heavy cream, you can use half and half plus a touch of extra Parmesan cheese. For a lighter version, try ground turkey instead of beef. You can swap the mozzarella for fontina or provolone for a different cheesy character. Whole wheat or gluten free penne both work nicely for those with dietary needs.
Serving Suggestions
For big appetites, serve this hearty pasta with garlic bread to soak up every drop of sauce. A green salad tossed with lemon vinaigrette adds a bright crisp complement. Steamed broccoli or sautéed spinach also balance the richness on the plate. At home I often double the recipe knowing leftovers make the best lunches.
Cultural and Historical Context
This dish mixes classic Italian pasta traditions with the bold flavors loved in American comfort food. The creamy garlic butter cheese sauce is a twist inspired by Italian American restaurants while penne remains a staple of traditional Italian cooking. Despite its new world spin, the soul of the dish is pure heartwarming nostalgia.

Frequently Asked Questions
- → Can I use a different type of pasta?
Yes, you can substitute penne with other types of pasta like rigatoni, fusilli, or farfalle. Cooking times may vary, so ensure the pasta is cooked al dente.
- → How do I prevent my cheese sauce from becoming clumpy?
To avoid clumps, make sure to continuously stir the cheese into the sauce over low heat and use freshly shredded cheese, which melts more smoothly.
- → Can I make this dish ahead of time?
While best served fresh, you can prepare this dish ahead of time, refrigerate it, and reheat it gently on the stove with a splash of broth or cream to refresh the sauce.
- → What can I use instead of beef broth?
For a different flavor or dietary preference, you can use chicken broth, vegetable broth, or even water with a splash of soy sauce to enhance the flavor.
- → Can I make this dish vegetarian?
Absolutely! Simply omit the ground beef and use vegetable broth instead of beef broth. You can also add sautéed mushrooms or other vegetables for added texture and flavor.
- → How can I add more spice to this dish?
To spice it up, increase the amount of red pepper flakes or add a pinch of cayenne pepper for a mild kick. Adjust to your taste preferences.