
This classic Cajun Chicken and Shrimp Pasta combines tender proteins with a rich, creamy sauce that has just the right amount of spice. The recipe evolved from countless attempts to capture that perfect restaurant-style pasta dish, and it's now a treasured family favorite that brings everyone rushing to the dinner table.
The Perfect Balance of Flavors
The marriage of zesty Cajun spices and silky cream sauce creates an irresistible combination. This versatile dish works equally well for special occasions or casual family dinners, delivering restaurant-quality results from your own kitchen.
Essential Ingredients
- Pasta: Traditional fettuccine provides the ideal base
- Chicken: Dark meat thighs provide rich flavor
- Shrimp: Fresh wild-caught adds natural sweetness
- Bell Peppers: Multiple colors enhance presentation
- Onion: Sweet variety balances the spice
- Cajun Seasoning: The key flavor foundation
- Half & Half: Creates perfect sauce texture
- Chicken Broth: Adds depth of flavor
- Parmesan: Fresh-grated melts smoothly
- White Wine: Deglazes and enhances sauce
- Olive Oil: Use high-quality for best results
Preparation Method
- Begin with Pasta
- Start well-salted water boiling for the pasta base
- Prepare Proteins
- Season and cook chicken and shrimp separately until perfectly done
- Sauté Vegetables
- Cook peppers and onions in the seasoned pan
- Create Sauce
- Combine wine, broth, cream, and cheese for the signature sauce
- Final Assembly
- Incorporate all components into the finished dish
Professional Tips
Watch shrimp closely while cooking - remove them slightly early as they'll finish in the sauce. Reserve pasta cooking water to adjust sauce consistency as needed.

Customization Options
The recipe welcomes additions like fresh mushrooms or tender spinach. Adjust spice levels to taste. The versatile base recipe adapts easily to personal preferences.
Suggested Accompaniments
Serve alongside warm garlic bread to soak up the sauce. A crisp green salad provides fresh contrast. A chilled white wine pairs beautifully for special occasions.
Storage Guidelines
Store refrigerated for up to three days. Revive leftover portions with a touch of cream or broth when reheating to restore the original sauce consistency.
Dietary Modifications
Substitute coconut milk for dairy-free needs. Use gluten-free pasta varieties as needed. The core flavors remain intact with these adaptations.
Signature Elements
The characteristic Cajun spice profile, luxurious cream sauce, and perfectly cooked proteins create an expertly balanced dish that consistently impresses.

Nutritional Benefits
This dish provides quality protein from both chicken and shrimp, along with vegetables for added nutrition. Using whole grain pasta increases fiber content.
Scaling the Recipe
Double ingredients for larger gatherings. Use an oversized pan and maintain proper temperature control when cooking increased quantities.
Protein Variations
Consider substituting andouille sausage for additional Cajun flavor. Seafood-only versions work well, or focus on chicken for those avoiding shellfish.
Seasoning Suggestions
Adjust Cajun seasoning to preference. Offer additional spices tableside including red pepper flakes and hot sauce for customized heat levels.
Vegetarian Adaptation
Create a meatless version using mushrooms, zucchini, and cherry tomatoes. Add crispy tofu for protein if desired.

Time-Saving Strategies
Incorporate pre-cooked rotisserie chicken and cleaned shrimp to reduce preparation time without compromising flavor.
Make-Ahead Options
Prepare extra sauce for freezing. Thaw and combine with fresh pasta for quick future meals.
Presentation Tips
Serve in white pasta bowls garnished with fresh herbs and lemon wedges. The colorful ingredients create an appealing presentation.
Creative Leftovers
Transform extras into a baked pasta dish topped with melted mozzarella for a different dining experience.
Universal Appeal
The combination of simple preparation and sophisticated flavor profile makes this recipe a reliable favorite for both everyday meals and special occasions.

Frequently Asked Questions
- → Why should I choose chicken thighs?
- Thighs stay juicier and cook up more tender compared to breast meat, though you can swap with breasts if you prefer.
- → What kind of shrimp works best?
- To get the best taste and perfect texture, go for large, peeled, and deveined wild-caught shrimp.
- → Is there a substitute for the wine?
- You can use extra chicken broth instead. However, wine deepens the flavor of the sauce.
- → Why do I need to reduce the liquids?
- This helps concentrate the flavors and thickens the base before mixing in the cream.
- → Which pasta is good for this dish?
- Fettuccine works great, but you can easily use linguine, spaghetti, or another long pasta.