Savory Cajun Pasta

Featured in Heartwarming Main Course Recipes.

This easy Cajun-style pasta blends juicy chicken, shrimp, and crisp peppers with a creamy Parmesan wine sauce. It’s ready in just 40 minutes!
Rose
Updated on Sat, 15 Mar 2025 16:21:08 GMT
A close-up shot of pasta loaded with creamy sauce, shrimp, tender chicken, and colorful peppers, topped with parsley. Pin it
A close-up shot of pasta loaded with creamy sauce, shrimp, tender chicken, and colorful peppers, topped with parsley. | lovelylifewithrose.com

This classic Cajun Chicken and Shrimp Pasta combines tender proteins with a rich, creamy sauce that has just the right amount of spice. The recipe evolved from countless attempts to capture that perfect restaurant-style pasta dish, and it's now a treasured family favorite that brings everyone rushing to the dinner table.

The Perfect Balance of Flavors

The marriage of zesty Cajun spices and silky cream sauce creates an irresistible combination. This versatile dish works equally well for special occasions or casual family dinners, delivering restaurant-quality results from your own kitchen.

Essential Ingredients

  • Pasta: Traditional fettuccine provides the ideal base
  • Chicken: Dark meat thighs provide rich flavor
  • Shrimp: Fresh wild-caught adds natural sweetness
  • Bell Peppers: Multiple colors enhance presentation
  • Onion: Sweet variety balances the spice
  • Cajun Seasoning: The key flavor foundation
  • Half & Half: Creates perfect sauce texture
  • Chicken Broth: Adds depth of flavor
  • Parmesan: Fresh-grated melts smoothly
  • White Wine: Deglazes and enhances sauce
  • Olive Oil: Use high-quality for best results

Preparation Method

Begin with Pasta
Start well-salted water boiling for the pasta base
Prepare Proteins
Season and cook chicken and shrimp separately until perfectly done
Sauté Vegetables
Cook peppers and onions in the seasoned pan
Create Sauce
Combine wine, broth, cream, and cheese for the signature sauce
Final Assembly
Incorporate all components into the finished dish

Professional Tips

Watch shrimp closely while cooking - remove them slightly early as they'll finish in the sauce. Reserve pasta cooking water to adjust sauce consistency as needed.

A close-up of a skillet filled with creamy fettuccine pasta, shrimp, and pieces of chicken, garnished with red peppers and parsley. Pin it
A close-up of a skillet filled with creamy fettuccine pasta, shrimp, and pieces of chicken, garnished with red peppers and parsley. | lovelylifewithrose.com

Customization Options

The recipe welcomes additions like fresh mushrooms or tender spinach. Adjust spice levels to taste. The versatile base recipe adapts easily to personal preferences.

Suggested Accompaniments

Serve alongside warm garlic bread to soak up the sauce. A crisp green salad provides fresh contrast. A chilled white wine pairs beautifully for special occasions.

Storage Guidelines

Store refrigerated for up to three days. Revive leftover portions with a touch of cream or broth when reheating to restore the original sauce consistency.

Dietary Modifications

Substitute coconut milk for dairy-free needs. Use gluten-free pasta varieties as needed. The core flavors remain intact with these adaptations.

Signature Elements

The characteristic Cajun spice profile, luxurious cream sauce, and perfectly cooked proteins create an expertly balanced dish that consistently impresses.

A close-up of a bowl of fettuccine pasta mixed with shrimp, chicken, and bell peppers, garnished with parsley and grated cheese. Pin it
A close-up of a bowl of fettuccine pasta mixed with shrimp, chicken, and bell peppers, garnished with parsley and grated cheese. | lovelylifewithrose.com

Nutritional Benefits

This dish provides quality protein from both chicken and shrimp, along with vegetables for added nutrition. Using whole grain pasta increases fiber content.

Scaling the Recipe

Double ingredients for larger gatherings. Use an oversized pan and maintain proper temperature control when cooking increased quantities.

Protein Variations

Consider substituting andouille sausage for additional Cajun flavor. Seafood-only versions work well, or focus on chicken for those avoiding shellfish.

Seasoning Suggestions

Adjust Cajun seasoning to preference. Offer additional spices tableside including red pepper flakes and hot sauce for customized heat levels.

Vegetarian Adaptation

Create a meatless version using mushrooms, zucchini, and cherry tomatoes. Add crispy tofu for protein if desired.

A creamy shrimp and chicken fettuccine dish garnished with parsley and mixed bell peppers in a black skillet. Pin it
A creamy shrimp and chicken fettuccine dish garnished with parsley and mixed bell peppers in a black skillet. | lovelylifewithrose.com

Time-Saving Strategies

Incorporate pre-cooked rotisserie chicken and cleaned shrimp to reduce preparation time without compromising flavor.

Make-Ahead Options

Prepare extra sauce for freezing. Thaw and combine with fresh pasta for quick future meals.

Presentation Tips

Serve in white pasta bowls garnished with fresh herbs and lemon wedges. The colorful ingredients create an appealing presentation.

Creative Leftovers

Transform extras into a baked pasta dish topped with melted mozzarella for a different dining experience.

Universal Appeal

The combination of simple preparation and sophisticated flavor profile makes this recipe a reliable favorite for both everyday meals and special occasions.

A close-up view of a delicious pasta dish featuring fettuccine, shrimp, and chicken, garnished with herbs and red peppers. Pin it
A close-up view of a delicious pasta dish featuring fettuccine, shrimp, and chicken, garnished with herbs and red peppers. | lovelylifewithrose.com

Frequently Asked Questions

→ Why should I choose chicken thighs?
Thighs stay juicier and cook up more tender compared to breast meat, though you can swap with breasts if you prefer.
→ What kind of shrimp works best?
To get the best taste and perfect texture, go for large, peeled, and deveined wild-caught shrimp.
→ Is there a substitute for the wine?
You can use extra chicken broth instead. However, wine deepens the flavor of the sauce.
→ Why do I need to reduce the liquids?
This helps concentrate the flavors and thickens the base before mixing in the cream.
→ Which pasta is good for this dish?
Fettuccine works great, but you can easily use linguine, spaghetti, or another long pasta.

Seafood with Cream Sauce

A flavorful combo of Cajun-spiced shrimp, chicken, and peppers wrapped in a creamy wine and Parmesan sauce.

Prep Time
10 Minutes
Cook Time
30 Minutes
Total Time
40 Minutes
By: Rose

Category: Main Dishes

Difficulty: Intermediate

Cuisine: Italian

Yield: 6 Servings (1 big skillet)

Dietary: ~

Ingredients

01 3/4 pound of pasta (fettuccine) that hasn’t been cooked yet.
02 1 pound of shrimp, already peeled and cleaned.
03 1 pound of boneless and skinless chicken thighs, chopped into tiny bits.
04 1 tablespoon of Cajun spice blend.
05 3 tablespoons of olive oil.
06 2 bell peppers sliced into thin strips.
07 1 big onion, halved, then sliced.
08 3/4 cup of dry white wine.
09 1 cup of chicken stock.
10 1 clove of garlic, finely chopped.
11 3/4 cup of heavy cream or Half & Half.
12 3/4 cup of Parmesan cheese, grated.
13 Chopped fresh parsley for decoration.

Instructions

Step 01

Boil your pasta in salted water until it’s got a slight bite. Drain the water and set it to the side.

Step 02

Using oil, cook your shrimp and chicken seasoned with Cajun spices until properly cooked. Take them out of the pan.

Step 03

In the same pan, sauté your sliced peppers and onions for about 5 minutes. Remove them when ready.

Step 04

Boil your wine and chicken broth together until about 75% of the liquid is gone. Stir in the garlic, cream, and Parmesan cheese until it’s smooth and velvety.

Step 05

Put the cooked veggies, chicken, shrimp, and pasta back into the sauce. Mix everything so it coats well. Sprinkle parsley over the top before serving.

Notes

  1. Try to get shrimp that’s caught in the wild.
  2. Chicken thighs stay juicier and tender compared to chicken breast.
  3. Make sure you cook down the sauce enough to get the right texture.

Tools You'll Need

  • A big, non-stick skillet.
  • A pot for boiling pasta.

Allergy Information

Please check ingredients for potential allergens and consult a health professional if in doubt.
  • Contains dairy from the cream and Parmesan.
  • Shellfish (shrimp).
  • Pasta has wheat.

Nutrition Facts (Per Serving)

It is important to consider this information as approximate and not to use it as definitive health advice.
  • Calories: 643
  • Total Fat: 27 g
  • Total Carbohydrate: 51 g
  • Protein: 43 g